Kingshan BJ7520 Resin-A Core Domestic Solution for Peptide Drug Purification

1. Adopts a special functional group modification process, increasing the selective adsorption capacity for target peptides by 30% compared with traditional media, and can accurately distinguish target components from impurities with similar structures; 2. Optimized pore size and specific surface area design, with an adsorption capacity of 86 mg/mL and a 40% increase in dynamic adsorption rate, suitable for high-load processing in large-scale production; 3. Excellent chemical stability, resistant to a wide pH range of 2-12 and common eluents, with a regeneration efficiency of over 96% and a cyclic service life of more than 12 cycles; 4. Supports an integrated "pretreatment-adsorption-gradient elution-regeneration" process solution, which can be directly connected without modifying existing equipment.
A biopharmaceutical company applied BJ7520 resin to the purification of a new hypoglycemic peptide drug, and after 9 months of operation: 1. Peptide purity increased from 92% to 99.93%, with an impurity removal rate of 99.2%, passing the on-site verification of drug registration by the National Medical Products Administration; 2. Target peptide yield improved from 85% to 95.6%, single-batch output increased by 12.5%, and annual new output value exceeded 8 million yuan; 3. Purification process steps were simplified from 5 to 3, production cycle was shortened from 18 hours to 10 hours, with efficiency increased by 44%; 4. Chemical reagent consumption was reduced by 28%, wastewater discharge by 22%, and comprehensive production cost by 25%.




